James M Olcese Ph.D.

Associate Professor
james.olcese@med.fsu.edu
850-645-1479
Appointment: Dept. of Biomedical Sciences
Courses: Clinical Neuroscience

Organ Physiology

Research Lab Site
Biosketch
Dr. Olcese has served as a visiting assistant professor at Marquette University in Milwaukee, Wis., as an assistant professor and associate professor at Rhodes College in Memphis, Tenn., and as a professor and group leader at the Institute for Hormone & Fertility Research at the University of Hamburg Medical School in Hamburg, Germany.
Education
B.S., Biology, Emory University, Atlanta, Ga.

Ph.D., Physiology, Marquette University, Milwaukee, Wis.

Postdoctoral fellow, Dept. of Anatomy, University of Mainz, Germany

Service
Past member of the Editorial Boards of Journal of Endocrinology and Journal of Pineal Research. Currently Associate Editor for Frontiers in Molecular Neuroscience. Member of the Board of the European Biological Rhythms Society (since 1990) and member of the “Melatonin Receptor Nomenclature and Classification (MRNC) Subcommittee” of the International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR) since 2004.
Honors/Awards
Dean's Award for Outstanding Faculty Research - Rhodes College, Memphis, TN (1987)

Alexander von Humboldt Research Fellowship - University of Hamburg, Germany (1989-90)

Memberships
Society for Neuroscience USA

European Pineal and Biological Rhythms Society

Sigma Xi

New York Academy of Science

Society for Research on Biological Rhythms

Endocrine Society

Research Focus
Circadian Physiology (endocrine rhythms, sleep disorders); Neuroendocrine mechanisms (hormonal systems, reproductive function, GnRH); Alzheimer dementia and melatonin
Publications
1) Olcese J, Sikes HE and D Resuehr 2006 Induction of mPer1 mRNA expression in immortalized gonadotropes by gonadotropin-releasing hormone (GnRH): Involvement of protein kinase C and MAP kinase signaling. Chronobiology International 23: 143-150.

2) Resuehr D, Sikes HE and J Olcese 2006 Effect of melatonin and caloric restriction on the temporal expression of murine hypothalamic transcripts. J. Neuroendocrinology 18: 279-289

3) Resuehr D, Wildemann U, Sikes HE and J Olcese 2007 E-box regulation of gonadotropin-releasing hormone (GnRH) receptor expression in immortalized gonadotrope cells. Molec. Cell. Endocrinol. 278: 36-43

4) Sharkey J and J Olcese 2007 Transcriptional inhibition of oxytocin receptor expression in human myometrial cells by melatonin involves protein kinase C signaling. J. Clin. Endocrinol. Metabol. 92: 4015-19

5) Sharkey J, Puttaramu R, Word RA and J Olcese 2009 Melatonin synergizes with oxytocin to enhance contractility of human myometrial smooth muscle cells. J. Clin. Endocrinol. Metabol. 94: 421-427

6)Olcese JM, Cao C, Mori T, Mamcarz MB, Maxwell A, Runfeldt MJ, Wang L, Zhang C, Lin X , Zhang G and GW Arendash 2009 Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease. J. Pineal Res. (in press)

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