Nanomate TriVersa is an automated nanoelectospray sample delivery system that integrates LC/MS, chip-based infusion, and fraction collection. Each sample is delivered to the mass spectrometer via a separate nozzle, thus preventing potential analyte carryover.  Some of the Nanomate TriVersa applications include rapid identification of proteins from 2D gels, analysis of protein post-translational modifications and non-covalent interactions.

Instrument specs

Advion's Product Information Sheet (2.3MB)

More information

See vendor's site: Advion

Suggested Reading

• Advion website (login required)
• Zhang S, Van Pelt CK., Chip-based nanoelectrospray mass spectrometry for protein characterization. Expert Rev. Proteomics,2004, 1, 449-68.
• Zhang S, Van Pelt CK, & Henion JD., Automated chip-based nanoelectrospray- mass spectrometry for rapid identification of proteins separated by two dimensional gel electrophoresis, Electrophoresis, 2003, 24, 3620- 3632.
• Zhang S., Van Pelt C.K., &Wilson D.B., Quantitative determination of noncovalent binding interactions using automated nanoelectrospray mass spectrometry, Anal. Chem., 2004, 75, 3010-3018.
• Keetch C.A., Hernanndez H., Sterling A., Baumert M., Allen M.H., & Robinson C.V., Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target, Anal. Chem. 2004, 75, 4937-4941.
• Zamfir A., Vakhrushev S., Sterling A., Niebel H.J., Allen M., & Peter-Katalinic J., Fully automated chip-based mass spectrometry for complex carbohydrate system analysis, Anal. Chem., 2004, 76, 2046-2054.
• Corkery L.J., Pang H., Schneider B.B., Covey T.R., & Siu K.W., Automated nanospray using chip-based emitters for the quantitative analysis of pharmaceutical compounds, J. Am. Soc. Mass. Spectrom., 2005, 16, 363-9.

Protocols and procedures

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